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. 2019 Aug 19;9:11986. doi: 10.1038/s41598-019-48502-9

Table 2.

Details of durations used for the main criterion in each group.

Variable Overall Placebo Group Timolol Group P-value
Total epistaxis duration before treatment
M − 3 n 58 29 29 0.47
median (min − max) 108.5 (0–825) 83 (0–545) 143 (22.58–825)
Mean (SD) 172.47 (177.43) 155.6 (150.97) 189.33 (201.76)
M − 2 n 58 29 29 0.99
median (min − max) 122.5 (15–600) 118 (15–600) 129 (22.15–561)
Mean (SD) 167.74 (139.12) 172.1 (151.46) 163.38 (128.13)
M − 1 n 58 29 29 0.97
median (min − max) 155.5 (0–580) 128 (0–520) 163 (12.5–580)
Mean (SD) 183.04 (145.42) 180.79 (146.39) 185.29 (146.99)
Total epistaxis duration after treatment (3 months)
M + 1 n 58 29 29 0.62
median (min − max) 125 (11–612) 100 (14–505) 143 (11–612)
Mean (SD) 162.3 (137.13) 154.42 (136.36) 170.18 (139.84)
M + 2 n 58 29 29 0.54
median (min − max) 94 (6–605) 95 (12–513) 93 (6–605)
Mean (SD) 171.95 (162.32) 180.61 (160.99) 163.29 (166.02)
M + 3 n 58 29 29 0.96
median (min − max) 109.5 (7–599) 97 (7–475) 126 (10.2–599)
Mean (SD) 158.87 (146.98) 147.89 (126.31) 169.85 (166.66)
Mean epistaxis duration at 3 months
Before treatment n 58 29 29 0.78
median (min − max) 136.5 (19.08–642.33) 132 (24–555) 141.67 (19.08–642.33)
Mean (SD) 174.57 (144.72) 169.5 (143.08) 179.65 (148.71)
After treatment n 58 29 29 0.98
median (min − max) 123.17 (12.4–583.67) 101.67 (14–491.67) 125.33 (12.4–583.67)
Mean (SD) 164.92 (141.94) 162.06 (134.45) 167.78 (151.39)
Difference Before - After n 58 29 29 0.81
median (min − max) −18.17 (−230.33–134.33) −16.33 (−230.33–134.33) −20 (−177.33–125)
Mean (SD) −9.65 (68.61) −7.44 (71.23) −11.87 (67.08)