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. 2019 Aug 19;9:11966. doi: 10.1038/s41598-019-48333-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Tissue specificity of PGR binding motifs in granulosa cells and uterus. PGR binding sites were divided by specificity to either granulosa cells, uterus or present in both (as in Fig. 7B) for motif analysis. Bars indicate fold enrichment to background. Circles indicate –log(pvalue). Among motifs found by HOMER that belong to the same TF family, the most conservative sequences are selected and ranked by fold enrichment compared to background frequency.