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. 2019 Aug 19;9:11982. doi: 10.1038/s41598-019-47322-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Distributions of systolic blood pressure for Japanese men in their 30 s (n = 169) and 60 s (n = 316). The blue line represents the distribution of systolic blood pressure in Japanese men during their 30 s (mean ± S.D. = 123.2 ± 12.5 mmHg). The red line represents the distribution of systolic blood pressure in Japanese men during their 60 s (mean ± S.D. = 137.4 ± 18.4 mmHg). Data were derived from the 2014 National Health and Nutrition Examination Survey in Japan: https://www.e-stat.go.jp/stat-search/files?page=1&layout=datalist&lid=000001151595.(b) PHQ-9 distributions during middle adulthood. The distributions of PHQ-9 scores were similar among the middle adulthood group (30 s, 40 s, 50 s, and 60 s) in the US general population. Data were derived from the 2009‒2014 United States National Health and Nutrition Examination Survey (n = 15,847). 10.3389/fpsyt.2018.00390.