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. 2019 Aug 13;7:568. doi: 10.3389/fchem.2019.00568

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Copyright © 2019 Ostacolo, Di Sarno, Musella, Ciaglia, Vestuto, Pepe, Merciai, Campiglia, Gomez Monterrey and Bertamino.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CHART 2 — Aminomethylation of Aromatic Compounds with DCM and Amines^a,b. ^aReaction conditions: 3.0 mmol of CH₂Cl₂, 1.0 mmol of substrate, 1.5 mmol of amine, 2.0 mmol of NaH, 5 mL of CH₃CN, under ultrasound irradiation at room temperature for 120 min. ^bIsolated yield.