Figure 1.
S. aureus Strains Isolated from Patients with Atopic Dermatitis Are Diverse
(A) Variable presence of toxin, resistance, and adhesion-associated genes. Heatmap display of Basic Local Alignment Search Tool (BLAST) results for specific gene sequence presence in each isolate compared with the reference strain USA300 FPR3757. Sequence identity (%) presented in KEY (right).
(B) Maximum likelihood phylogenetic tree from a concatenated open reading frame dataset, rooted with SaMSHR1132 (branch not shown). Bacterial isolates from patients with atopic dermatitis analyzed with 30 previously sequenced “sign-post” genomes that are publicly available. Values on or near the node are bootstrap support percentages; values of 100% are indicated with a red circle. The branch length reference is in substitutions/site.