Table 1.
Characteristics of S. aureus Strains Isolated from Patients with Atopic Dermatitis
| Isolate # | EASI Score |
Culture Site | Bacterial Burden | MRSA? | MLST(CC; spa Type) | Antibiotic Resistance | |
|---|---|---|---|---|---|---|---|
| Low EASI | AD1 | 4.5 | S | Few | MSSA | ST8(CC8; t1892) | EM |
| AD2 | 0.2 | S | Moderate | MSSA | ST1(CC1; t922) | ||
| AD3 | 2.4 | P | Moderate | MRSA | ST22(CC22; new) | OX | |
| AD4 | 3.1 | N | Few | MSSA | ST5 (CC5; t002) | EM | |
| AD5 | 2 | S | Moderate | MSSA | ST15(CC15; new) | EM | |
| High EASI | AD6 | 33.3 | S | Heavy | MSSA | ST9 (CC109; t209) | EM |
| AD7 | 33.6 | S | Few | MSSA | ST? (CC188; t189) | ||
| AD8 | 40 | S | Heavy | MSSA | ST5 (CC5; t045) | ||
| AD9 | 28.5 | S | Few | MRSA | ST8 (CC8; t008) | CM, EM, LVX, OX, TC | |
| AD10 | 40 | S | Heavy | MSSA | ST? (CC6; new) | EM |
CC, clonal complex; CM, clindamycin; EM, erythromycin; LVX, levofloxacin; MRSA, methicillin-resistant Staphylococcus aureus; N, nares; OX, oxacillin; P, perianal; S, skin; TC, tetracycline.
S. aureus isolates from low and high EASI (Eczema Area and Severity Index) score groups listed with site of culture, methicillin sensitivity, Ridom type, MLST, antibiotic resistance, and associated clinical EASI score.
Spa types labeled as “new” could not be assigned to a recognized type in the Ridom database, but had characteristics consistent with spa variable repeat regions.