Figure 8.

GFP-TMEM88 Shifts the Accumulation of β-Catenin to Perinuclear MVB Even in the Absence of DVL

(A) DVL TKO 293T cells were transfected with plasmid vectors expressing GFP-TMEM88 or GFP; 24 h after transfection, the cells were fixed, immunostained with β-catenin antibody, and nuclei stained with DAPI.

(B) Quantification of localization of β-catenin of Figure 8A. ∗∗∗Chi-squared p value: 7.63 × 10⁻¹¹. For GFP, N = 46. For GFP-TMEM88, N = 50.

(C) Quantification of nuclear β-catenin of Figure 8A. For GFP, N = 46. For GFP-TMEM88, N = 50. Graphs show mean ± SEM. ^∗∗p < 0.01.