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. 2019 Jul 30;25:104324. doi: 10.1016/j.dib.2019.104324

Fig. 4.

Fig. 4

Evaluation of Ki67 expression on human CPC stimulated in vitro by the hAFS secretome. Evaluation of proliferative response from different CPC subpopulations after treatment with 80μg/ml of either hAFS-CM or hNCTC-CM, compared to untreated cells (Ctrl) by Ki67 staining. All values are expressed as mean ± s. e.m of the percentage of Ki67-positive cells of at least n = 3 experiments. hCPC (Ctrl: 27.82 ± 0.66%; hAFS-CM: 45.01 ± 0.82%; hNCTC-CM: 29.50 ± 0.71%. ****p < 0.0001). fSca-1+ hCPC (Ctrl: 17.73 ± 2.13%; hAFS-CM: 26.52 ± 1.46%; hNCTC-CM: 15.13 ± 2.44%. *p < 0.05 p = 0.011; **p < 0.01, p = 0.0011). hEPDCc (Ctrl: 3.87 ± 0.60%; hAFS-CM: 9.57 ± 1.23%; hNCTC-CM: 4.52 ± 0.95%; *p < 0.05, p = 0.0131). hEPDCs (Ctrl: 8.83 ± 1.20%; hAFS-CM: 21.17 ± 2.08%; hNCTC-CM: 7.37 ± 1.01%; **p < 0.01, p = 0.0083 and p = 0.0018).