Histological examination of skin biopsy from left arm showing features of severe Sweet’s syndrome. (A, B) On low magnification, there is a dense superficial and mid dermal infiltrate and massive subepithelial oedema imparting a pseudobullous appearance. (C) On medium magnification, collection of purpura with dense inflammation in the dermis can be seen. (D) On high magnification, the dermal infiltrate is composed of neutrophils with marked red cell extravasation. There are prominent blood vessels with oedema of their walls but no areas of fibrinoid necrosis. H&E, original magnification (A, B) 10× (C) 20× and (D) 40×.