Fig. 2.

Maximum-likelihood phylogeny of C. difficile ST1 genomes (n=1379). Clinical isolates from healthcare facilities in northern Arizona (this study, in red) are present in six different lineages (1–6). The presence of the GyrA Thr82Ile mutation conferring quinolone resistance is indicated by blue branches (light blue indicates FQR1 and dark blue indicates FQR2 identified in a previous study [9]). Seven isolates from Arizona sequenced as part of previous studies are identified with purple triangles. Boxes highlight lineages (labelled 1 and 6) that contain multiple isolates from healthcare facilities in northern Arizona.