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. 2019 Jun 14;117(2):281–295. doi: 10.1016/j.bpj.2019.04.041

Figure 8.

Figure 8

The effect of slowly increasing electrical stimulation on the preferential activation of small fibers. (A) The stimulation current needed to generate an action potential for different shapes and durations of slowly increasing stimulation current is shown. (B) The membrane potential corresponding to an extracellular field alteration when applying the electrical current with the ExpB shape is shown (see Table 4). The nerve fiber model was placed underneath the electrode in the middle of the epidermis (Aδ model) or the dermis (Aβ model). (C) The average current needed to generate an action potential for different spatial location is illustrated in the figure. The error bars represent the SD. To see this figure in color, go online.