Table 1.
Relationship between LINC00460 level and clinicopathologic features (N = 123)
| Characteristics | No. of Patients | LINC00460 ΔCta Mean ± SD | Non-parametric test value | p value | |
|---|---|---|---|---|---|
| No. | % | ||||
| Age (years) | |||||
| ≥ 60 | 81 | 65.85 | 8.553 ± 2.175 | Z = 0.277 | 0.782 |
| < 60 | 42 | 34.15 | 8.607 ± 2.906 | ||
| Gender | |||||
| Male | 84 | 68.29 | 8.645 ± 2.758 | Z = 0.386 | 0.700 |
| Female | 39 | 31.71 | 8.412 ± 1.555 | ||
| Tumor Size (cm) | |||||
| ≤ 4 | 73 | 59.35 | 8.745 ± 2.548 | Z = 0.608 | 0.543 |
| > 4 | 50 | 40.65 | 8.319 ± 2.268 | ||
| Lymph Node Metastasis | |||||
| pN1 to pN3 | 63 | 51.22 | 8.022 ± 2.210 | Z = 2.436 | 0.015 * |
| pN0 | 60 | 48.78 | 9.231 ± 2.635 | ||
| TNM Stage | |||||
| I | 11 | 8.94 | 9.991 ± 3.331 | H = 4.052 | 0.256 |
| II | 28 | 22.76 | 9.087 ± 2.559 | ||
| III | 19 | 15.45 | 8.147 ± 2.719 | ||
| IV | 65 | 52.85 | 8.233 ± 2.028 | ||
| Pathological Differentiation | |||||
| Well | 85 | 69.11 | 8.810 ± 2.122 | Z = 2.094 | 0.036 * |
| Moderately/poorly | 38 | 30.89 | 8.038 ± 2.990 | ||
| Tumor Site | |||||
| Tongue | 42 | 34.15 | 8.812 ± 1.928 | H = 3.411 | 0.492 |
| Gingival | 36 | 29.27 | 8.293 ± 2.304 | ||
| Cheek | 25 | 20.32 | 8.122 ± 2.246 | ||
| Floor of Mouth | 6 | 4.88 | 8.802 ± 1.548 | ||
| Oropharynx | 14 | 11.38 | 8.775 ± 3.268 | ||
| Local Invasion | |||||
| No | 87 | 70.73 | 8.550 ± 2.604 | Z = 0.183 | 0.854 |
| Yes | 36 | 29.27 | 8.624 ± 2.011 | ||
| Tumor Type | |||||
| Primary | 105 | 85.37 | 8.723 ± 2.493 | Z = 1.782 | 0.075 |
| Recurrence | 18 | 14.63 | 7.684 ± 1.907 | ||
Abbreviations: SD standard deviation, pN pathological lymph node status
aThe ΔCt value was determined by subtracting the GAPDH Ct value from the LINC00460 Ct value. Smaller ΔCt values indicate higher expression. *p<0.05