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. 2019 Jun 25;117(2):355–368. doi: 10.1016/j.bpj.2019.06.017

Figure 4.

Figure 4

(a) [P]/[S] dynamics determined for mass-action and GEEK models for different initial substrate concentrations [S]init and different occupied volume fractions (ϕ) for the E. coli molecular weight distributions. The light dashed lines represent the dilute mass-action model, whereas the thin solid lines represent a population of 100 resampled GEEK models. (b) Time to half-equilibrium teq/2 as a function of the occupied volume fraction for different initial substrate concentrations [S]init is shown. The colors of the lines denote the different initial concentrations: blue corresponds to [S]init = [S]ref/4, yellow to [S]init = [S]ref, green to [S]init = 2[S]ref, and red to [S]init = 4[S]ref.