Fig. 3.

High-salt elevates endothelial inflammation via NLRP3. a-d Quantification of mRNA levels of E-selectin, ICAM-1, VCAM-1 and MCP-1 in TA and AA of ApoE−/− mice fed with a normal or high-salt diet. e-h Quantification of mRNA levels of E-selectin, VCAM-1, ICAM-1, and MCP-1 in ECs treated with high-salt and transfected with Control siRNA or NLRP3 siRNA. i, j The adhesion of Calcein-labeled THP-1 monocytes in ECs treated with high-salt and transfected with Control siRNA or NLRP3 siRNA. All data were presented as mean ± SEM, N ≥ 3. *p < 0.05