Table 3.

Multivariate logistic regression analyses of circulating ESM-1 levels and CAD

	Unadjusted		Model 1		Model 2		Model 3
	OR (95%CI)	P-value	OR (95%CI)	P-value	OR (95%CI)	P-value	OR (95%CI)	P-value
ESM-1 (per 100 pg increase)	1.383 (1.247–1.534)	< 0.001**	1.314 (1.175–1.470)	< 0.001**	1.688 (1.226–2.323)	< 0.001*	1.633 (1.179–2.262)	0.003

Dependent variable: CAD. Model 1: adjusted for age, sex, BMI, smoking, drinking. Model 2: adjusted for Model 1 + DBP, TG, TC, LDL, FBG, ALT and AST. Model 3: adjusted for Model 2 + AHI and LSaO₂

BMI Body mass index, DBP Diastolic blood pressure, TG Triglycerides, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, FBG Fasting blood glucose, ALT Alanine aminotransferase, AST Aspartate aminotransferase

**P < 0.001 in multivariate analysis, *P < 0.05 in multivariate analysis