Table 4.
Baseline demographics, CNS features, and SSS-8 of seven patients diagnosed with CNS infections
| Case | Gender | Age at SLE diagnosis (years) | Disease duration (months) | Neuropsychiatric symptoms | CSF examination | Hypocomplementemia | SSS-8 | Possible CNS infections | Final diagnosis | Etiology | Concordance of prejudge with final diagnosis | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pressure (mmH2O) | WBC (/μL) | PMN ratio (%) | Protein (g/L) | Glucose (mmol/L) | |||||||||||
| 1 | F | 35 | 1 | Fever, headache, hemiplegia | 310 | 580 | 94 | 1.07 | 4.23 | No | 6 | Yes | Brain abscess | Listeria monocytogenes | Yes |
| 2 | F | 37 | 2 | Fever, headache, hemiplegia | 260 | 59 | 1 | 0.6 | 2.8 | No | 4 | Yes | Brain abscess | Unknown | Yes |
| 3 | F | 54 | 5 | Fever, cognitive dysfunction, consciousness disturbance | 135 | 690 | 92.4 | 8.83 | 0.9 | Yes | 5 | Yes | Meningoencephalitis | Unknown | Yes |
| 4 | F | 53 | 1 | Fever, headache, vomiting, consciousness disturbance | > 330 | 269 | 4.9 | 2.42 | 2.7 | Yes | 5 | Yes | Meningitis | Mycobacterium | Yes |
| 5 | F | 12 | 3 | Fever, headache | 160 | 50 | 12 | 1.5 | 2.0 | Yes | 5 | Yes | Meningitis | Fusarium | Yes |
| 6 | F | 12 | 122 | Fever, headache, vomiting | 120 | 1054 | 98 | 2.78 | 0.1 | No | 7 | Yes | Meningitis | Gram-negative bacillus | Yes |
| 7 | M | 26 | 60 | Fever, headache, vomiting, consciousness disturbance | 230 | 6 | 0 | 0.45 | 2.7 | Yes | 2 | No | Brain abscess | Listeria monocytogenes | No |
CNS central nervous system, SLE systemic lupus erythematosus, NPSLE neuropsychiatric lupus erythematosus, CSF cerebrospinal fluid, WBCs white blood cells, PMN polymorphonuclear leukocyte, SSS-8 simplified scoring system with 8 items