Fig. 6.

Global 5-mC and 5-hmc patterns in the neocortex. a, c Representative pictures of 5-mC staining (a) and 5-hmc staining (c) in the neocortex of TLE patients and controls. Scale bars represent 100 μm. b, d ImageJ quantification of the integrated density of 5-mc staining (b) and 5-hmc staining (d) in the neocortex. n = 6–8 per group. Error bars show SEM. **p < 0.01 and ***p < 0.001 for significant difference to CTRL. CTRL = control; HS⁻ = TLE without HS; HS⁺ = TLE with HS; HS⁺FS⁺ = TLE with HS and FS