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. 2019 Aug 20;20:29. doi: 10.1186/s12865-019-0310-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Influence of age on S. pneumoniae serotype-specific IgG antibodies. Summation of total S. pneumoniae serotype antibodies was positively associated with age in a subnormal IgG1 non-responders and b subnormal IgG3 responders