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. Author manuscript; available in PMC: 2019 Aug 20.
Published in final edited form as: Semin Cell Dev Biol. 2009 Feb 13;20(2):225–230. doi: 10.1016/j.semcdb.2009.02.003

Fig. 1.

Fig. 1

A phylogenetic tree of the various SPPs that have been studied to date is shown. This tree was created using the multiple alignment sequence program found at http://3w.molgen.mpg.de/. Protein sequences used to generate the alignment and the phylogenetic tree are shown in parenthesis. Note that such an alignment suggests that one of the Drosophila Melanogaster SPPs (NP 651437) should probably be renamed SPPL3. The phylogenetic tree demonstrates that the SPP and SPPL3 orthologs are more closely related then the SPPL2 family members.