Table 2.
Effect of 2-mercaptobenzimidazole 1 and derivatives 2–5 on acetic acid-induced cramps in mice.
| Products | Doses (mg/kg) | Number of cramps in 10 min | Percentage of inhibition (%) |
|---|---|---|---|
| 1 | 200 | 26.20 ± 3.96∗ | 33.67 ± 10.03∗ |
| 2 | 200 | 25.00 ± 3.53∗ | 36.70 ± 08.95∗ |
| 3 | 200 | 19.60 ± 3.78∗ | 50.37 ± 09.57∗ |
| 4 | 200 | 17.60 ± 4.82∗ | 55.44 ± 12.22∗ |
| 5 | 200 | 19.75 ± 4.24∗ | 50.00 ± 10.81∗ |
| Acetylsalicylic acid | 100 | 09.60 ± 1.50∗∗ | 75.69 ± 03.79∗∗ |
| Control | — | 39.50 ± 2.60 | — |
∗ p < 0.05; ∗∗p < 0.0001 compared to control.