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SML1 fractions obtained by LPLC and tested on human leukaemia cells (HL-60).
| LPLC fractions | Yields (%) | EC50 (μg/mL) |
|---|---|---|
| F1 | 23.7 | 6.5 ± 0.9 |
| F2 | 30.3 | 12.8 ± 1.3 |
| F3 | 3.6 | 5.5 ± 0.4 |
| F4 | 1.9 | 3.8 ± 0.3 |
| F5 | 1.7 | 5.4 ± 0.3 |
| F6 | 4.7 | 4.1 ± 0.3 |
| F7 | 11.4 | 143.5 ± 34.1 |
| F8 | 4.6 | 37.9 ± 10.7 |
Cytotoxic activity was expressed by EC50 (mean values ± SEM). Vinblastine was used as positive control (EC50 = 12.2 ± 1.3 nM).
