Table 3.
White matter tracts with higher values (>5%, p < 0.05) in fractional anisotropy (FA) in ASD patients after 12 months of therapies (G2) compared to patients at diagnosis (G1) by TBSS.
| White matter tracts | % of significant FA regional differences post-therapy |
FA patients at diagnosis (N = 9) Mean ± SD |
FA patients after therapies (N = 9) Mean ± SD |
|---|---|---|---|
| JHU ATLAS | |||
| RIFOF | 32.268 | 0.405 ± 0.033 | 0.428 ± 0.031 |
| LCST | 32.086 | 0.544 ± 0.026 | 0.566 ± 0.026 |
| Fminor | 31.589 | 0.493 ± 0.039 | 0.515 ± 0.039 |
| RCST | 30.898 | 0.561 ± 0.028 | 0.584 ± 0.028 |
| RATR | 26.682 | 0.366 ± 0.020 | 0.381 ± 0.024 |
| RSLF | 18.736 | 0.382 ± 0.024 | 0.394 ± 0.029 |
| LIFOF | 16.225 | 0.383 ± 0.030 | 0.408 ± 0.033 |
| Fmajor | 14.101 | 0.416 ± 0.044 | 0.449 ± 0.043 |
| LATR | 9.172 | 0.371 ± 0.023 | 0.391 ± 0.028 |
| LSLF | 7.330 | 0.414 ± 0.068 | 0.438 ± 0.069 |
| ICBM ATLAS | |||
| BCC | 46.51 | 0.592 ± 0.040 | 0.612 ± 0.032 |
| LRLIC | 43.21 | 0.506 ± 0.033 | 0.531 ± 0.036 |
| RRLIC | 42.23 | 0.483 ± 0.040 | 0.495 ± 0.041 |
| RPCR | 39.79 | 0.412 ± 0.026 | 0.424 ± 0.029 |
| LACR | 38.42 | 0.365 ± 0.039 | 0.393 ± 0.042 |
| RPTR* | 36.94 | 0.489 ± 0.046 | 0.522 ± 0.041 |
| RACR | 34.09 | 0.368 ± 0.029 | 0.392 ± 0.032 |
| GCC | 30.66 | 0.638 ± 0.040 | 0.657 ± 0.037 |
| LPCR | 26.32 | 0.421 ± 0.037 | 0.442 ± 0.034 |
| RALIC | 21.69 | 0.476 ± 0.019 | 0.497 ± 0.024 |
| LEC | 21.25 | 0.346 ± 0.022 | 0.370 ± 0.018 |
| RSLF | 15.26 | 0.394 ± 0.026 | 0.405 ± 0.028 |
| LPLIC | 14.37 | 0.613 ± 0.027 | 0.636 ± 0.026 |
| SCC | 13.31 | 0.679 ± 0.015 | 0.694 ± 0.020 |
| Fx (cres)/ RST | 10.56 | 0.432 ± 0.037 | 0.441 ± 0.038 |
| LCP | 9.90 | 0.561 ± 0.019 | 0.591 ± 0.022 |
| RPLIC | 9.77 | 0.626 ± 0.027 | 0.642 ± 0.020 |
| RSS* | 6.10 | 0.432 ± 0.038 | 0.458 ± 0.0.40 |
| LSLF | 5.77 | 0.396 ± 0.021 | 0.041 ± 0.023 |
LSLF, Left Superior longitudinal fasciculus; RSLF, Right Superior longitudinal fasciculus; Fminor, Forceps minor; LIFOF, Left Inferior fronto-occipital fasciculus; Fmajor, Forceps major; RIFOF, Right Inferior fronto-occipital fasciculus; LCST, Left corticospinal tract; RCST, Right corticospinal tract; LATR, left anterior thalamic radiation; BCC, Body of corpus callosum; RATR, Right anterior thalamic radiation; LEC, Left external capsule; Fx, Fornix (cres); LCP, Left Cerebral peduncle, LACR, Left anterior corona radiata; RACR, Right anterior corona radiata; RSS*, Right sagittal stratum (inferior longitudinal fasciculus and inferior fronto-occipital fasciculus); RPLIC, Right Posterior limb internal capsule; RST, Right stria terminalis; GCC, Genu of corpus callosum; SCC, Splenium of corpus callosum; RPCR, Right posterior corona radiata; RPTR*, Right posterior thalamic radiation (plus optic radiation); LPCR, Left posterior corona radiata; RRIC, Right retro-lenticular internal capsule; LRLIC, Left retro-lenticular internal capsule, RALIC, Right anterior limb of internal capsule; LPLIC, Left posterior limb of internal capsule.