Table 3.
Multivariate analysis of overall, cancer-specific, and progression-free survival.
| OS | CSS | PFS | ||||
|---|---|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | HR (95% CI) | p value | |
| CASZ1 | ||||||
| Low vs. high | 0.589 (0.437-0.794) | 0.001 | 0.526 (0.367-0.754) | <0.001 | 0.558 (0.417-0.747) | <0.001 |
| WHO/ISUP grade | ||||||
| 1, 2 vs. 3, 4 | 1.775 (1.317-2.391) | <0.001 | 3.387 (2.129-5.389) | <0.001 | 1.866 (1.386-2.513) | <0.001 |
| T category | ||||||
| T1, T2 vs. T3, T4 | 1.855 (1.378-2.498) | <0.001 | 2.538 (1.768-3.645) | <0.001 | 2.431 (1.813-3.259) | <0.001 |
| N category | ||||||
| N0/Nx vs. N1 | 5.417 (3.037-9.662) | <0.001 | 6.190 (3.346-11.451) | <0.001 | 3.918 (2.157-7.116) | <0.001 |
| M category | ||||||
| M0 vs. M1 | 6.497 (4.636-9.105) | <0.001 | 9.385 (6.429-13.702) | <0.001 | 7.677 (5.469-10.778) | <0.001 |
OS: overall survival; CSS: cancer-specific survival; PFS: progression-free survival; HR: hazard ratio; CI: confidence interval.