Table 2.
Top 10 functional enrichment categories within the top 250 genes by ERHS from the entire study, as summarized by REVIGO from the ToppFun results.
| Ontology ID | Ontology type | Description | p-value | Dispensability | Frequency | Uniqueness |
|---|---|---|---|---|---|---|
| GO:0043209 | Cellular component | Myelin sheath | 4.80E-06 | 0 | 0.01% | 0.929 |
| GO:0048193 | Biological process | Golgi vesicle transport | 5.56E-05 | 0 | 0.04% | 0.736 |
| GO:2001025 | Biological process | Positive regulation of response to drug | 4.14E-04 | 0 | 0.00% | 0.75 |
| GO:0016556 | Biological process | mRNA modification | 8.13E-04 | 0 | 0.02% | 0.817 |
| GO:0004971 | Molecular function | AMPA selective glutamate receptor activity | 8.17E-04 | 0 | 0.00% | 0.939 |
| GO:0031267 | Molecular function | Small GTPase binding | 9.25E-04 | 0 | 0.03% | 0.854 |
| GO:0018660 | Molecular function | 4-Hydroxyphenylacetate, NADH: oxygen oxidoreductase (3-hydroxylating) activity | 2.79E-03 | 0 | 0.00% | 0.335 |
| GO:0002474 | Biological process | Antigen processing and presentation of peptide antigen via MHC class I | 5.15E-03 | 0 | 0.06% | 0.971 |
| GO:0048475 | Cellular component | Coated membrane | 5.18E-03 | 0 | 0.10% | 0.942 |
| GO:0060076 | Cellular component | Excitatory synapse | 9.83E-03 | 0 | 0.00% | 0.854 |