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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Ultrasound Med Biol. 2019 Apr 16;45(7):1762–1776. doi: 10.1016/j.ultrasmedbio.2019.02.004

Figure 7: (Color online) Generation of stable and inertial cavitation and trends with rarefactional pressure.

Figure 7:

(A-D) Acoustic stimulation of PCCAs resulted in the generation of substantial stable cavitation (SCD) and inertial cavitation (ICD) for all acoustic conditions tested. The persistence of this cavitation over 30 seconds varied between conditions. In general, SCD and ICD was most persistent at the low-pressure conditions (300 or 400 kPa) with short pulse length (20 cycles). Total SCD and ICD dose was calculated as the area under the cavitation curves over 30 seconds. (E) For the 20 cycle conditions, we found significant inverse trend between rarefactional pressure and total SCD+ICD dose and SCD dose. (F) This trend held true for SCD+ICD, SCD and ICD doses for the 40 cycle conditions. All data presented as mean±SD with n=3 replicates.