Figure 1. Transitions during spermatogenesis at the cellular, nuclear and chromosome organization levels.
Left panel shows a section through a mouse testis and seminiferous tubule indicating the location of male germline cells at different stages of differentiation, from spermatogonia to mature sperm. Center panels describe the organization of nuclei and chromosomes in the same stages of spermatogenesis. Right panels display Hi-C heatmaps covering the length of a single chromosome and showing intra-chromosome interactions in the nuclei of the corresponding cell types.
