Skip to main content

View full-text article in PMC

. 2019 Aug 8;9(8):e025884. doi: 10.1136/bmjopen-2018-025884

Table 3.

Biochemical data

Variable	Baseline			Reperfusion 2 hours			Follow-up (5 days)
Variable	GSH	Placebo	P value	GSH	Placebo	P value	GSH	Placebo	P value
H₂O₂ µM, mean±SD Δ	40.6±8.4	43.6±11.6	0.305	28.4±12	42.8±14.1	0.0003	24±7	39.5±17.3	0.0001
H₂O₂ µM, mean±SD Δ	40.6±8.4	43.6±11.6	0.305	−12.1±15.2	−0.7±17.9	0.03	−16.6±11.0	−4.1±20.14	0.009
8-iso-PGF2α pmol/L, mean±SD Δ	214.6±81.1	211.9±92.1	0.91	163.6±44.7	217.6±51.6	0.0003	159.9±34.2	213.1±50.9	0.0001
8-iso-PGF2α pmol/L, mean±SD Δ	214.6±81.1	211.9±92.1	0.91	−50.9±92.9	−3.3±1.29	0.02	−54.6±62.1	−1.2±115.7	0.02
HBA %, mean±SD Δ	43.6±7.4	43.4±11.9	0.94	57.9±8.6	43.9±8.7	0.0001	62.9±10.5	45.2±13.0	0.0001
HBA %, mean±SD Δ	43.6±7.4	43.4±11.9	0.94	+14.9±5.5	+0.4±14.9	0.0004	+19.4±10.2	+1.8±17.1	0.0001
NO µM, mean±SD Δ	16.3±5.7	16.5±4.7	0.89	27.7±7.2	22.4±10	0.0356	35.5±8.1	23.5±15.5	0.0013
NO µM, mean±SD Δ	16.3±5.7	16.5±4.7	0.89	+11.4±6.8	+5.8±10.5	0.05	+19.2±9.7	+7.0±14.7	0.002

8-iso-PGF2α, 8-iso-prostaglandin-F2α; GSH, glutathione; H₂O₂, hydrogen peroxide; HBA, H₂O₂ break-down activity; NO, nitric oxide.