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. 2019 Aug 16;12:6565–6576. doi: 10.2147/OTT.S202698

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© 2019 Wang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Silencing Paip1 expression inhibited GC cell migration by preventing EMT.

Notes: (A) The motility of the cells was evaluated by a wound healing assay in MGC-803 and SGC-7901 cells treated with siRNA1 and siCON. (B, C) The effects of Paip1 downregulation on cell migration and invasion were determined by Transwell assays in MGC-803 and SGC-7901 cells treated with siRNA1 and siCON. (D) EMT-related protein expression was analyzed in MGC-803 and SGC-7901 cells treated with siRNA1 and siCON. Each column shows the mean of three independent experiments. Each bar represents the mean ± SD. *p<0.05, **p<0.01.

Abbreviations: siCON, non-targeting siRNA; siRNA, small interfering RNA.