Table 1.
Baseline characteristic of 31 studies included in mortality meta-analysis
| Name of study | Target population | Sample size N |
Women, number (%) | Mean BMI (kg/m2) | Mean initial weight (kg) | Mean age (years) | Intervention duration (years) |
Follow-up duration (years) |
Deaths |
| Summary statistic weighted mean | 615 | 346 (56) | 32.5 | 87.2 | 53.8 | 2.39 | 2.49 | 19 | |
| ACHIEVE41 | Overweight/obese with mental illness | 291 | 146 (50) | 36.3 | 102.7 | 45.3 | 1.5 | 1.5 | 5 |
| ADAPT42 | Overweight/obese knee osteoarthritic older persons | 318 | 229 (72) | 34.3 | 93.8 | 68.5 | 1.5 | 1.5 (8 for mortality) |
45 |
| ALIFE@WORK20 | Overweight/obese | 1386 | 457 (33) | 29.6 | 92.1 | 43 | 0.5 | 2 | 3 |
| BE-WELL21 | Obese with asthma | 330 | 234 (71) | 37.5 | 104.2 | 47.6 | 1 | 1 | 0 |
| CLIP43 | Overweight/obese older with limited mobility and cardiovascular disease or dysfunction | 288 | 193 (67) | 32.8 | 91.9 | 67.1 | 1.5 | 1.5 | 3 |
| Da Qing19 | Impaired glucose tolerance | 530 | 244 (46) | 25.8 | _ | 45 | 6 | 6 | 11 |
| DPP31 | Overweight/obese with elevated fasting glucose | 2161 | 1491 (69) | 34.1 | 94.2 | 50.4 | 2.8 | 2.8 | 8 |
| EDIPS-Newcastle44 | Overweight/obese with impaired glucose tolerance | 102 | 61 (60) | 33.8 | 92 | 57.1 | 3.1 | 3.1 | 3 |
| E-LITE45 | Overweight/obese persons with prediabetes or metabolic syndrome | 241 | 113 (47) | 32 | 93.8 | 52.9 | 1.25 | 1.25 | 0 |
| HEALTH TRACK32 | Overweight and obese Australians | 377 | 279 (74) | 32 | 125.2 | 45 | 1 | 1 | 0 |
| HCP22 | Hypertension | 118 | 42 (36) | – | 77 | 56 | 4 | 4 | 3 |
| IDEA46 | Overweight/obese with osteoarthritis knee | 454 | 327 (72) | 33.6 | 93 | 66 | 1.5 | 1.5 | 0 |
| IDPP-147 | Indian and Pakistani origin with impaired glucose tolerance | 269 | 62 (23) | 26 | _ | 45.6 | 2.5 | 2.5 | 2 |
| LEAN23 | Overweight/obese women with treated breast cancer | 100 | 100 (100) | 33.1 | 87.5 | 59 | 0.5 | 1 | 0 |
| LISA48 | Overweight/obese postmenopausal women with breast cancer history who are currently taking letrozole | 338 | 338 (100) | 31.3 | 82 | 61 | 2 | 2 | 2 |
| Look AHEAD29 | Overweight/obese with type 2 diabetes | 5145 | 3087 (60) | 36 | 101 | 58.8 | 9.6 | 9.6 | 376 |
| NEW49 | Overweight/obese postmenopausal women | 439 | 439 (100) | 30.9 | 83.6 | 58 | 1 | 1 | 1 |
| ORBIT28 | Obese African-American women | 213 | 213 (100) | 39.2 | 104.9 | 46 | 1.5 | 1.5 | 1 |
| Patrick50 | Overweight/obese men | 441 | 0 (0) | 34.2 | 104.7 | 43.9 | 1 | 1 | 2 |
| PODOSA51 | Indian or Pakistani origin with impaired glucose tolerance test | 171 | 92 (54) | 30.5 | 80.3 | 52.5 | 3 | 3 | 1 |
| POWER18 | Obese with cardiovascular risk factors | 276 | 176 (64) | 36.6 | 103.4 | 54 | 2 | 2 | 0 |
| SLIM52 | Impaired glucose tolerance | 147 | 72 (49) | 29.8 | 85.5 | 56.9 | 4.1 | 4.1 | 1 |
| STRIDE53 | Overweight/obese taking antipsychotic agents | 200 | 144 (72) | 38.3 | 107.7 | 47.2 | 1 | 1 | 2 |
| Swedish Bjorknas54 | Metabolic syndrome | 145 | 83 (57) | 29.8 | 85.8 | 54.4 | 3 | 3 | 0 |
| TAIM55 | Overweight/obese hypertensive | 200 | 102 (51) | _ | 87.7 | 48.3 | 4.5 | 4.5 | 2 |
| TOHP I56 | Normal to high blood pressure | 564 | 180 (32) | 29.5 | 89.8 | 42.8 | 1.5 | 1.5 | 2 |
| TOHP II57 | Overweight/obese persons that are normotensive or hypertensive | 2382 | 810 (34) | 30.9 | 93.6 | 43.6 | 3 | 3 | 12 |
| TONE30 | Overweight/obese elderly hypertensive persons | 585 | 304 (52) | 31.2 | 87.8 | 65.5 | 2.5 | 2.5 (12 mortality) |
101 |
| Trento24 | Type 2 diabetes | 112 | 50 (45) | 28.8 | 77.8 | 61.5 | 2 | 2 | 4 |
| Villareal58 | Older obese | 107 | 67 (63) | 37.2 | 100.8 | 69.7 | 1 | 1 | 0 |
| WOMAN59 | Overweight/obese postmenopausal women | 508 | 508 (100) | 30.8 | 81.7 | 57 | 3 | 4 | 3 |