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. Author manuscript; available in PMC: 2020 Aug 19.
Published in final edited form as: Chem Res Toxicol. 2019 Aug 2;32(8):1722–1731. doi: 10.1021/acs.chemrestox.9b00230

Figure 9. NAD(P)H utilization in DHA metabolism.

Figure 9

A. Glycolytic (Embden-Meyerhof) pathway showing DHA’s entry into the 3-carbon metabolic pathway. Utilization of NAD(P)H and ATP is highlighted in red. B. Autofluorescent images of endogenous NADH and NADPH in untreated and 5 mM DHA treated cells. C. Quantification of fluorescent signal for untreated and 5 mM DHA treated cells. Each time point has its own untreated control to account for changes in NAD(P)H due to medium consumption during the DHA exposure time. Representative images are shown in B and scale bar is 50 µm.