Table 2.
Effect of Vitex negundo extracts on serum hormones in letrozole induced PCOS rat.
| Parameter (mg/dl) | NC | DC | VNA 200 | VNA 400 | VNE 200 | VNE 400 |
|---|---|---|---|---|---|---|
| Estradiol | 22.06 ± 2.11 | 09.24 ± 1.62 | 18.06 ± 1.84# | 20.06 ± 1.46# | 16.82 ± 2.11 | 19.69 ± 2.61# |
| Progesterone | 30.68 ± 0.62 | 20.32 ± 1.02* | 24.44 ± 0.06# | 27.68 ± 1.99# | 23.68 ± 2.12 | 24.68 ± 1.99# |
| Testosterone | 32.66 ± 1.42 | 45.68 ± 0.38* | 37.68 ± 2.42# | 34.24 ± 1.44# | 42.66 ± 1.98 | 40.66 ± 1.42 |
Values are expressed as Mean ± SEM (n = 6).
As evaluated by two way ANOVA followed by Bonferroni tests.
(NC: Normal control, DC: Disease control, VNA 200: Aqueous extract of Vitex negundo 200 mg/kg, VNA 400: Aqueous extract of Vitex negundo 400 mg/kg, VNE 200: Hydroalcoholic extract of Vitex negundo 200 mg/kg, VNE 400: Hydroalcoholic extract of Vitex negundo 400 mg/kg).