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. Author manuscript; available in PMC: 2019 Aug 20.
Published in final edited form as: Nanomedicine (Lond). 2018 Dec 21;14(6):727–752. doi: 10.2217/nnm-2018-0436

Figure 4. Cellular uptake investigation.

Figure 4

(A) Representative confocal fluorescence image of U-87 MG cells showing FITC-Nut-Mag-SLNs uptake after 24 h of incubation (nanoparticles in green, f-actin in red, nuclei in blue). (B) Prussian blue staining of U-87 MG cells after 24 h of incubation with Nut-Mag-SLNs (on the left). The image shows blue precipitates in the perinuclear area due to the presence of SPIONs upon Nut-Mag-SLN internalization. Nontreated cells are reported as control (on the right).

Nut-Mag-SNLs: Nutlin-loaded magnetic solid lipid nanoparticles; SPIONs: Superparamagnetic iron oxide nanoparticles.