Table 8.
SGPT levels of M. musculus on day 15, 22, and 30 (D15, D22, and D30) which previously, on D 1-7, received daily 250 mg/kg bw PC (B1), on D1-7 received daily 250 mg/kg bw PC and on D8-29 were given daily 55 (B2), 110 (B3), and 220 (B4) mg/kg bw E2TL respectively, while the controls received only the solvent in the same manner (B0).
| Group of experimental animals | N | SGPT concentration in the blood of M. musculus (U/L), on |
||
|---|---|---|---|---|
| D15 | D22 | D30 | ||
| B0: Control, normal. | 1 | 60.00 | ||
| B1: 250 mg/kg bw PC. | 1 | 318.25 | ||
| B2: 250 mg/kg bw PC, 55 mg/kg bw E2TL. | 3 | 294.88 ± 13.91a | 225.06 ± 2.73d | 163.77 ± 2.81g |
| B3: 250 mg/kg bw PC, 110.0 mg/kg bw E2TL. | 3 | 230.73 ± 4.62b | 158.03 ± 4.75e | 119.66 ± 3.80h |
| B4: 250 mg/kg PC, 220 mg/kg bw E2TL. | 3 | 197.18 ± 5.73c | 100.03 ± 2.42f | 89.94 ± 1.70i |
Note: PC=Paracetamo; E2TL = ethanolic extract of Tylophora villosa leaves; SGPT = serum glutamate pyruvate transaminase; Rates followed by the same letters (a,b) are not significantly different data addressing the same column and the same line (p < 0.05).