Table 9.
SGOT levels of M. musculus on day 15, 22, and 30 (D15, D22, and D30) which previously, on D 1-7, received daily 250 mg/kg bw PC (B1), on D1-7 received daily 250 mg/kg bw PC and on D8-29 were given daily 55 (B2), 110 (B3), and 220 (B4) mg/kgbw E2TL respectively, while the controls received only the solvent in the same manner (B0).
| Group of experimental animals | N | SG0T concentration in the blood of M. musculus (U/L), on |
||
|---|---|---|---|---|
| D15 | D22 | D30 | ||
| B0: Control, normal. | 1 | 100.00 | ||
| B1: 250 mg/kg bw PC | 1 | 510.15 | ||
| B2: 250 mg/kg bw PC, 55 mg/kg bw E2TL. | 3 | 498.75 ± 4.68a | 395.34 ± 4.33d | 231.82 ± 7.80g |
| B3: 250 mg/kg bw PC, 110 mg/kg bw E2TL. | 3 | 380.03 ± 5.42b | 289.34 ± 6.67e | 194.46 ± 0.55h |
| B4: 250 mg/kg bw PC, 220 mg/kg bw E2TL. | 3 | 291.07 ± 6.28c | 190.03 ± 2.42f | 135.03 ± 2.00i |
Note: PC=Paracetamo; E2TL = ethanolic extract of Tylophora villosa leaves; SGOT = serum glutamate oxaloacetate transaminase. Rates followed by the same letters (a,b) are not significantly different data addressing the same column and the same line (p < 0.05).