Table 5.
Group | Treatment (mg/Kg) | Mean increase in paw volume (ml) |
% decrease in volume | |||
---|---|---|---|---|---|---|
0 h | 1 h | 2 h | 3 h | |||
1 | Control | 1.15 ± 0.08 | 1.67 ± 0.14 | 1.88 ± 0.14 | 1.96 ± 0.15 | – |
2 | Aspirine | 1.12 ± 0.16 | 1.27 ± 0.16 | 1.40 ± 0.17 | 1.35 ± 0.11 | 68.08 |
3 | 50% ethanol | 1.19 ± 0.06 | 1.39 ± 0.22 | 1.59 ± 0.20 | 1.52 ± 0.14 | 54.58 |
4 | Methanol | 1.13 ± 0.18 | 1.44 ± 0.24 | 1.50 ± 0.14 | 1.69 ± 0.26 | 37.64 |
Data were analyzed using ANOVA and expressed as mean ± S.D (n = 6) followed by Dunnett's test and the difference between means was regarded significant at (P < 0.05). Here 0 h represent the volume of paw taken before the injection of carrageenan in rat paw whereas 1 h, 2 h and 3 h represents the volume of paw taken after 1 h, 2 h and 3 h of carrageen injection in planar surface of right hind paw.