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. 2019 Aug 20;9:12123. doi: 10.1038/s41598-019-48315-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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PCA analysis of metabolites in serum and urine from Asic3^+/+ mice [ICS-induced experimental fibromyalgia model (P10) vs controls (B)]. ¹H-NMR- and LC-MS/MS-based metabolites were identified by metabolomic comparison between P10 and B. PCA plots were based on ¹H-NMR data for serum (A) and urine (B) from B (green) and P10 groups (red) and LC-MS/MS data for serum (C) and urine (D).