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. 2019 Aug 20;10:3741. doi: 10.1038/s41467-019-11387-3

Table 1.

Association of PM2.5 exposure with the peak bilirubin levels on the basis of an increase of 1.0 μg per m3 (95 % CI) in exposure to PM2.5

Exposure intervals (μg per m3) Risk in peak bilirubin levels (mg per dL) Confidence lower limit (mg per dL) Confidence upper limit (mg per dL) P value
(0, 10) 0.848 −0.574 2.269 0.157
(10, 35) 0.076 0.027 0.125 0.003
(35,75) 0.029 0.014 0.044 0.031
(75, 200) 0.009 0.002 0.016 0.008
>200 0.01 −0.008 0.028 0.435

For PM2.5 concentrations ∈ [10, 35] μg per m3, a 1.0 μg per m3 increase in PM2.5 concentrations was associated with a 0.076 mg per dL (95% CI: 0.027–0.125) rise in the peak bilirubin level. For a 1.0 μg per m3 increase in PM2.5 concentration, the peak bilirubin level increased by 0.029 mg per dL (95% CI: 0.014–0.044) for PM2.5 concentrations ∈ (35, 75] μg per m3, and by 0.009 mg per dL (95% CI: 0.002–0.016) for PM2.5 concentrations ∈ (75, 200] μg per m3. The relationship between PM2.5 concentrations and the neonatal jaundice risk nearly plateaued at concentrations exceeding 200 μg per m³, such that an additional increase in pollution concentration was not statistically significantly associated with a further increase in bilirubin level