Skip to main content
. 2019 Aug 20;10(9):630. doi: 10.1038/s41419-019-1733-8

Fig. 6. Bioinformatic analysis of PPD and survival analysis of key proteins in HCC.

Fig. 6

a Volcano plot of the differentially expressed proteins between PPD-treated and untreated cancer cells. Red and green dots indicate the up- and downregulation of proteins, respectively. b Protein interaction network of PPD. c GO analysis of differentially expressed proteins. d KEGG analysis of differentially expressed proteins. e Kaplan–Meier curve showing the 10-year survival of TCGA LIHC samples classified by STAT3 or Twist1 expression. The correlation coefficient and P value are shown. f Correlation analysis of STAT3 with Twist1 in TCGA LIHC samples. The correlation coefficient and P value are shown. g Schematic diagram of PPD blockage possible mechanism in EMT via targeting STAT3/Twist1 signaling