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. 2018 Sep 28;9(4):278–284. doi: 10.1016/j.jtcme.2017.08.002

Table 5.

Effect of methanol extract of Mucuna pruriens leaves on hypotonicity-induced haemolysis of sickle RBC (HbSS).

Treatment Conc. (μg/ml) Mean absorbance ± SD
Percentage inhibition of haemolysis(%)
Hypotonic solution Isotonic solution
Control - 0.530 ± 0.00 a 0.129 ± 0.00 b
Extract 100 0.519 ± 0.00 a 0.039 ± 0.00 a 2.24
200 0.493 ± 0.01 a 0.041 ± 0.00 a 7.57
400 0.420 ± 0.00 b 0.354 ± 0.02 c 62.50
600 0.330 ± 0.01 c 0.301 ± 0.02 c 87.34
800 0.301 ± 0.01 c 0.274 ± 0.02 c 89.45
Indomethacin 200 0.269 ± 0.00 c 0.161 ± 0.00 b 85.02

Values are expressed as mean ± SD (n = 3). Mean values having different letters as superscripts down the column are considered significantly different (p < 0.05).