Table 4.
Univariable and multivariable associations for high degree of BG PVS and high degree of CS PVS.
| Unadjusted OR (95% CI), p-value | Adjusted OR (95% CI), p-value | |
|---|---|---|
| HIGH DEGREE OF BG PVS | ||
| Age | 1.070 (1.041–1.100), p < 0.001 |
1.075 (1.038–1.113), p < 0.001 |
| High CS PVS degree | 3.573 (1.851–6.896), p < 0.001 |
6.906 (3.024–15.774), p < 0.001 |
| Extensive periventricular WMH | 5.076 (2.653–9.713), p < 0.001 |
2.878 (1.298–6.379), p = 0.009 |
| Presence of microbleeds | 3.833 (1.918–7.660), p < 0.001 |
4.073 (1.869–8.877), p < 0.001 |
| HIGH DEGREE OF CS PVS | ||
| Alcohol drinking | 2.792 (1.455–5.358), p = 0.002 |
2.805 (1.451–5.422), p = 0.002 |
| Hyperlipidemia | 3.265 (1.424–7.485), p = 0.005 |
3.728 (1.582–8.783), p = 0.003 |
| High BG PVS degree | 4.299 (2.030–9.102), p < 0.001 |
6.293 (2.755–14.371), p < 0.001 |
| Strictly lobe microbleeds | 2.422 (1.229–4.773), p = 0.011 |
2.556 (1.285–5.085), p = 0.008 |
BG, basal ganglia; CI, confidence interval; CS, centrum semiovale; OR, odds ratio; PVS, enlarged perivascular spaces; WMH, white matter hyperintensities. Age effects are presented per year. Multivariable logistic regression model adjusted for age, gender, and hypertension.