Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 14;10:869. doi: 10.3389/fneur.2019.00869

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Zhu, Jiang, Tong, Xie, Zaharchuk and Wintermark.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Example of ultra-low dose 18F-florbetaben PET/MRI. Example of a positive 18F-florbetaben PET/MRI study acquired at 0.24 mCi, ~3% of a standard dose. Similar image quality is present in the 100% dose image and the synthetized image, which was created using a deep neural network along with MRI information such as T1, T2, and T2-FLAIR. As Alzheimer Disease studies are moving toward cognitively normal and younger patients, reducing dose would be helpful. Furthermore, tracer costs could be reduced if doses can be shared.