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Intracellular ROS rates were determined by flow cytometric analysis. Liraglutide attenuated the HG-induced ROS generation, to a certain extent. When PI3K/Akt pathway was blocked by LY, the inhibition of liraglutide was weakened. A total of 10 μM resveratrol was used as positive control. Data are presented as mean ± SD (n=3). *P<0.05. Abbreviation: PI3K, phosphoinositide 3-kinase .
