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. 2019 Aug 19;39(8):BSR20190109. doi: 10.1042/BSR20190109

Figure 6. GLP-1R knockdown significantly abolished liraglutide-induced activation of PI3K/Akt signaling in NPCs.

Figure 6

NPCs were transfected with negative control siRNA (SiCON) or GLP-1R siRNA (SiGLP-1R) before liraglutide treatment. (A) Representative Western blot picture. (B) Quantitation of GLP-1R expression standardised by GAPDH. (C) Quantitation analysis of ratio of p-Akt/total AKT. (D) Quantitation of cleaved caspase-3 expression standardised by GAPDH. Data are presented as mean ± SD (n=3). *P<0.05.

ns: non-significant.