Table 1.
Clinical and histopathologic characteristics of patients.
| Characteristics |
SEER Cohort (2006–2015) (n = 124,788) |
FDZSH Cohort (2009–2014) (n = 1,675) |
PKUPH Cohort (2000–2017) (n = 2,572) |
|---|---|---|---|
| Gender | |||
| Male | 64,448 (51.6) | 918 (54.8) | 1,391 (54.1) |
| Female | 60,340 (48.4) | 757 (45.2) | 1,181 (45.9) |
| Age, years | |||
| <65 | 46,348 (37.1) | 1,149 (68.6) | 1,471 (57.2) |
| ≥65 | 78,440 (62.9) | 526 (31.4) | 1,101 (42.8) |
| Location | |||
| Upper lobe | 75,130 (60.2) | 882 (52.7) | 1,313 (51.0) |
| Middle lobe | 5,888 (4.7) | 114 (6.8) | 174 (6.8) |
| Lower lobe | 37,072 (29.7) | 518 (30.9) | 763 (29.7) |
| Overlapping lesion of lung | 1,396 (1.1) | 155 (9.2) | 133 (5.2) |
| Unknown | 5,302 (4.3) | 6 (0.4) | 189 (7.3) |
| Histology | |||
| Squamous cell carcinoma | 42,380 (34.0) | 434 (25.9) | 497 (19.3) |
| Adenocarcinoma | 82,408 (66.0) | 1,241 (74.1) | 2,075 (80.7) |
| Grade | |||
| Well-differentiated; Grade I | 9,730 (7.8) | 34 (2.0) | 105 (4.1) |
| Moderately differentiated; Grade II | 32,599 (26.1) | 751 (44.8) | 1,222 (47.5) |
| Poorly differentiated; Grade III | 37,182 (29.8) | 626 (37.4) | 859 (33.4) |
| Undifferentiated; anaplastic; Grade IV | 1,023 (0.8) | 264 (15.8) | 386 (15.0) |
| Unknown | 44,254 (35.5) | – | |
| 8th AJCC/UICC stage | |||
| I | 34,259 (27.5) | 985 (58.8) | 1,644 (63.9) |
| II | 14,720 (11.8) | 304 (18.1) | 360 (14.0) |
| III | 27,190 (21.8) | 372 (22.2) | 484 (18.8) |
| IV | 48,619 (38.9) | 14 (0.9) | 84 (3.3) |
| Modified 8th stage | |||
| I | 33,803 (27.1) | 994 (59.4) | 1,614 (62.8) |
| II | 28,048 (22.5) | 535 (31.9) | 704 (27.4) |
| III | 25,647 (20.6) | 139 (8.3) | 188 (7.3) |
| IV | 37,290 (29.8) | 7 (0.4) | 66 (2.5) |
| Treatment | |||
| Surgery | 44,194 (35.4) | 1,675 (100) | 2,572 (100) |
| No surgery | 80,312 (64.4) | – | – |
| Unknown | 282 (0.2) | – | – |