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. 2019 Aug 14;9:772. doi: 10.3389/fonc.2019.00772

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Copyright © 2019 Mourad, Bilodeau, Roussy, Laramée, Boulianne, Rouette, Jouan, Gendron, Duval, Teira, Hébert, Bittencourt, Pastore, Landry and Cellot.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical presentation of AML in a 5-year-old patient with SDS syndrome. (A) Wright-Giemsa-stained cytologic preparation showing leukemic blasts collected from a bone marrow aspiration. Imaging was performed with an upright microscope (Zeiss AxioScope A.1) equipped with 20X/0.5 plan-neofluar and 100x/1.4 oil objectives and an Axiocam 105 color camera. Left and right panels, 200X and 1000X magnification, respectively. (B) Standard GTG-banded karyotype revealing no cytogenetic abnormality. (C) Flow cytometry analyses of bone marrow cells suggest a myeloid leukemia (CD45⁺ CD33⁺ CD34⁺CD117⁺) with high infiltration (>80%).