Table 4.

Representative biological processes related to downregulated proteins in breast cancer chemoresistance.

Cytoskeleton remodeling/cell adhesion

Collagen alpha-1(VII) chain; GRB2-associated-binding protein 1; integrin alpha V; keratin type II cytoskeletal 1; myosin regulatory light chain 2, skeletal muscle isoform; plectin

Blood coagulation

Fibrinogen alpha chain, fibrinogen beta chain

DNA repair/kinetochore assembly

Centromere protein F, centrosome-associated protein 350, DNA polymerase alpha catalytic subunit, microtubule-associated protein 1B, centrosomal protein of 290 kDa

Oxidative metabolism

ATPase family AAA domain-containing protein 3B; dynein heavy chain 1, axonemal; E3 ubiquitin protein ligase UBR5; ectonucleotide pyrophosphatase phosphodiesterase family member 1; glycogen phosphorylase, liver form; inorganic pyrophosphatase; sodium bicarbonate cotransporter 3; TBC1 domain family member 2A; tripeptidyl peptidase 2

Immune response_inflammation

Apolipoprotein C-II, RAC-gamma serine/threonine-protein kinase, regulator of G protein signaling 14

Immune response_humoral immune response

Ig heavy chain V-III region JON, Ig heavy chain V-III region VH26, Ig kappa chain VI region Roy, Ig lambda chain VI region WAH, Ig lambda chain V-VI region SUT, Ig mu heavy chain disease protein

Immune response_complement system

Complement C4B, complement component C8 gamma chain