Figure 5.

Optic nerves, brainstem, cord, and miscellaneous findings in Krabbe disease. A 7-month-old boy with early infantile Krabbe disease - T2 axial image (a) shows thickening of the prechiasmatic optic nerve which measures 4.6 mm. T1 sagittal image (b) shows the thickened optic nerve (white arrow) and moderate volume loss of midbrain (blue arrow) with hummingbird morphology and significant pontine volume loss (red arrow), axial T2 images of cervical cord in an adolescent onset case show hyperintensity of the lateral spinothalamic tract (white arrow). T2 sagittal image (d) in an early infantile onset subtype shows enlargement of cervical cord and lower brainstem (white arrows). Axial fluid-attenuated inversion recovery image (e) shows left frontal subdural collection with layered appearance (white arrow) with diffuse cerebral atrophy.