Effect of injection of CFA or saline into the lower lip on spontaneous activity and heat responses of whisker pad TG neurons. A, C, Typical peristimulus time histograms of spontaneous activities (A) and heat responses (C) of TG neurons. B, D, Mean firing frequency of spontaneous activity (B) and heat response (D). *p < 0.05, **p < 0.01 versus saline-injected (n = 5 in each group; Student's t test). Error bars indicate SEM.