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. 2011 May 11;31(19):7190–7198. doi: 10.1523/JNEUROSCI.1171-11.2011

Figure 3.

Figure 3.

A, Peak-dose dyskinesia (60–150 min after l-DOPA administration) in marmosets treated with l-DOPA and R-MDMA (1, 3, or 10 mg/kg) or vehicle. R-MDMA (3 and 10 mg/kg) significantly reduced the severity of peak-dose dyskinesia when compared to l-DOPA vehicle (both p < 0.05). B, Peak-dose dyskinesia (60–150 min after l-DOPA administration) in marmosets treated with l-DOPA and S-MDMA (1, 3, or 10 mg/kg) or vehicle. S-MDMA did not significantly alter the severity of peak-dose dyskinesia (p > 0.05). *p < 0.05 when compared to l-DOPA vehicle. The bars represent the median score for dyskinesia, and the dots represent the individual score of each animal. The maximal possible score (most severe disability) was 36. On the y-axis, 9 is mild, 18 is moderate, 27 is marked, and 36 is severe.