FIG 1.

US28 promotes cellular kinase phosphorylation in CD34⁺ HPCs. CD34⁺ HPCs infected with Ad-US28 were left untreated or were treated with PBS, RANTES (CCL5), or Fractalkine (CX₃CL1). HPCs infected with Ad-Empty that were treated with PBS were used as a background control for phosphorylation status. At 30 min posttreatment, cellular lysates were collected and analyzed using the PathScan RTK chip to quantify protein phosphorylation. The data are represented as fold change versus values for Ad-Empty and are representative of two independent experiments.